Depression, Loneliness, and Memory Problems Are Worse In Middle Age, But Only in America

Episode 271

3rd August 2026

Unpacking troubling data (for Yanks) with researcher Frank Infurna, plus a Mike Doughty update.

Episode notes

For most of the world, the advent of middle age does not make depression, loneliness, and memory issues more of a problem than earlier in life. In some countries, things actually get better. The only nation on earth where it all gets worse is right here in the USA. Arizona State University psychologist Frank Infurna has been researching this topic extensively and explains the uniquely American societal forces that are contributing to us being generally more miserable. It’s a lot of things beyond an individuals’ control: unstable job market, expensive health insurance tied to those unstable jobs, out of control housing and childcare costs, as well as current middle-agers being part of a sandwich generation. They often have to manage and fund expensive and complex eldercare for their parents while also helping their children make their way in a challenging world. Frank offers thoughts on what we can and cannot do about all this.

We also talk with musician Mike Doughty. Last time he was on, he was fresh out of in-patient psychiatric care and hitting the road with his once highly estranged band Soul Coughing. We find out how he’s doing now, how he made amends with his audience, and why an unplugged satellite dish matters so much.

Thank you to all our listeners who support the show as monthly members of Maximum Fun.

Check out our I’m Glad You’re Here and Depresh Mode merchandise at the brand new merch website MaxFunStore.com!

Hey, remember, you’re part of Depresh Mode and we want to hear what you want to hear about. What guests and issues would you like to have covered in a future episode? Write us at depreshmode@maximumfun.org.

Depresh Mode is on BlueSky, Instagram, Substack, and you can join our Preshies Facebook group.

Help is available right away.

The National Suicide Prevention Lifeline: 988 or 1-800-273-8255, 1-800-273-TALK

Crisis Text Line: Text HOME to 741741.

International suicide hotline numbers available here: https://www.opencounseling.com/suicide-hotlines

Help support this show and unlock bonus content! Become a member at https://maximumfun.org/joindepresh

In this episode...

Guests

  • Frank Infurna
  • Mike Doughty

About the show

Join host John Moe (The Hilarious World of Depression) for honest, relatable, and, yes, sometimes funny conversations about mental health. Hear from comedians, musicians, authors, actors, and other top names in entertainment and the arts about living with depression, anxiety, and many other common disorders. Find out what they’ve done to address it, what worked, and what didn’t. Depresh Mode with John Moe also features useful insights on mental health issues with experts in the field. It’s honest talk from people who have been there and know their stuff. No shame, no stigma, and maybe a few laughs.

Like this podcast? Then you’ll love John’s book, The Hilarious World of Depression.

Logo by Clarissa Hernandez.

People

How to listen

Stream or download episodes directly from our website, or listen via your favorite podcatcher!

Share this show

New? Start here...